首页> 外文OA文献 >Histopathological examination of specimens removed during directional coronary atherectomy in patients presenting with crescendo angina show mural thrombus.
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Histopathological examination of specimens removed during directional coronary atherectomy in patients presenting with crescendo angina show mural thrombus.

机译:进行性冠心病心绞痛的患者在定向冠状动脉粥样斑块切除术期间取出的标本的组织病理学检查显示壁血栓。

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摘要

Thrombus formation over a fissured coronary atheromatous plaque has been shown by post mortem histological examination to be the pathophysiological mechanism responsible for myocardial ischaemia in those patients who died following a crescendo pattern of angina. Histological examination of plaques responsible for a crescendo pattern of angina in patients who do not die has not been available until recently. We describe two patients who presented with a crescendo pattern of angina. A new technique of coronary revascularization, directional coronary atherectomy, produced symptomatic relief and resolution of myocardial ischaemia. Histological examination of material from the stenosis responsible for their myocardial ischaemia, obtained using this technique, confirmed thrombus formation overlying a fissured atheromatous plaque.
机译:尸检后的组织学检查表明,裂痕性冠状动脉粥样斑块上的血栓形成是导致心绞痛呈渐进型死亡的患者心肌缺血的病理生理机制。直到最近,尚无组织学检查可导致未死亡患者心绞痛呈渐进型斑块的组织学检查。我们描述了两名患者的心绞痛加重模式。冠状动脉血运重建的新技术,定向冠状动脉粥样硬化斑块切除术,可减轻症状并缓解心肌缺血。使用这种技术对引起其心肌缺血的狭窄材料进行组织学检查,证实血栓形成覆盖在裂开的动脉粥样斑块上。

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